Influence of L-lactate and low glucose concentrations on the metabolism and the toxin formation of Clostridioides difficile

Julia Danielle Hofmann; Rebekka Biedendieck; Annika-Marisa Michel; Dietmar Schomburg; Dieter Jahn; Meina Neumann-Schaal

doi:10.1371/journal.pone.0244988

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Open Access

Peer-reviewed

Research Article

Influence of L-lactate and low glucose concentrations on the metabolism and the toxin formation of Clostridioides difficile

Julia Danielle Hofmann,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Bioinformatics and Biochemistry, Technische Universität Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany
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Rebekka Biedendieck,

Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

Affiliations Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany, Institute of Microbiology, Technische Universität Braunschweig, Braunschweig, Germany
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Annika-Marisa Michel,

Roles Formal analysis, Methodology

Affiliations Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany, Institute of Microbiology, Technische Universität Braunschweig, Braunschweig, Germany
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Dietmar Schomburg,

Roles Conceptualization, Data curation, Project administration, Writing – review & editing

Affiliations Department of Bioinformatics and Biochemistry, Technische Universität Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany
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Dieter Jahn,

Roles Data curation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany, Institute of Microbiology, Technische Universität Braunschweig, Braunschweig, Germany
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Meina Neumann-Schaal

Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: meina.neumann-schaal@dsmz.de

Affiliations Department of Bioinformatics and Biochemistry, Technische Universität Braunschweig, Braunschweig, Germany, Braunschweig Integrated Centre of Systems Biology (BRICS), Braunschweig, Germany, Leibniz Institute DSMZ—German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany

https://orcid.org/0000-0002-1641-019X

⨯

Influence of L-lactate and low glucose concentrations on the metabolism and the toxin formation of Clostridioides difficile

Julia Danielle Hofmann,
Rebekka Biedendieck,
Annika-Marisa Michel,
Dietmar Schomburg,
Dieter Jahn,
Meina Neumann-Schaal

Published: January 7, 2021
https://doi.org/10.1371/journal.pone.0244988

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