Towards remote monitoring in pediatric care and clinical trials—Tolerability, repeatability and reference values of candidate digital endpoints derived from physical activity, heart rate and sleep in healthy children

• M. D. Kruizinga ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft

  * E-mail: mkruizinga@chdr.nl

  Affiliations Centre for Human Drug Research, Leiden, The Netherlands, Juliana Children’s Hospital, HAGA Teaching Hospital, The Hague, The Netherlands, Leiden University Medical Centre, Leiden, The Netherlands

  https://orcid.org/0000-0002-2054-2187

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• N. van der Heide,

  Roles Formal analysis, Investigation, Project administration, Writing – review & editing

  Affiliations Centre for Human Drug Research, Leiden, The Netherlands, Juliana Children’s Hospital, HAGA Teaching Hospital, The Hague, The Netherlands

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• A. Moll,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Centre for Human Drug Research, Leiden, The Netherlands, Juliana Children’s Hospital, HAGA Teaching Hospital, The Hague, The Netherlands

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• A. Zhuparris,

  Roles Data curation, Formal analysis, Visualization, Writing – review & editing

  Affiliation Centre for Human Drug Research, Leiden, The Netherlands

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• Y. Yavuz,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation Centre for Human Drug Research, Leiden, The Netherlands

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• M. L. de Kam,

  Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

  Affiliation Centre for Human Drug Research, Leiden, The Netherlands

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• F. E. Stuurman,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Centre for Human Drug Research, Leiden, The Netherlands, Leiden University Medical Centre, Leiden, The Netherlands

  https://orcid.org/0000-0002-0013-8355

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• A. F. Cohen,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Centre for Human Drug Research, Leiden, The Netherlands, Leiden University Medical Centre, Leiden, The Netherlands

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• G. J. A. Driessen

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Juliana Children’s Hospital, HAGA Teaching Hospital, The Hague, The Netherlands, Maastricht University Medical Centre, Maastricht, The Netherlands

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