Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds

• Vincent U. Gant,

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, United States of America

  https://orcid.org/0000-0003-3416-230X

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• Jacob J. Junco,

  Roles Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, United States of America

  https://orcid.org/0000-0002-2435-7739

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• Maci Terrell,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, United States of America

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• Raushan Rashid,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, United States of America

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• Karen R. Rabin

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: krrabin@texaschildrens.org

  Affiliation Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, United States of America

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