Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library

Kazunobu Yagi; Kazuya Mimura; Takuji Tomimatsu; Tatsuya Matsuyama; Yoko Kawanishi; Aiko Kakigano; Hitomi Nakamura; Masayuki Endo; Tadashi Kimura

doi:10.1371/journal.pone.0244684

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Open Access

Peer-reviewed

Research Article

Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library

Kazunobu Yagi,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Kazuya Mimura ,

Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

* E-mail: kazuya.med_ob-gyne@hotmail.co.jp

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan

https://orcid.org/0000-0002-0950-7110

⨯
Takuji Tomimatsu,

Roles Methodology, Supervision, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Tatsuya Matsuyama,

Roles Data curation, Investigation

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Yoko Kawanishi,

Roles Formal analysis, Supervision

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Aiko Kakigano,

Roles Methodology, Supervision

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Hitomi Nakamura,

Roles Data curation, Investigation, Supervision, Validation

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Masayuki Endo,

Roles Supervision

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Tadashi Kimura

Roles Supervision

Affiliation Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
⨯

Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library

Kazunobu Yagi,
Kazuya Mimura,
Takuji Tomimatsu,
Tatsuya Matsuyama,
Yoko Kawanishi,
Aiko Kakigano,
Hitomi Nakamura,
Masayuki Endo,
Tadashi Kimura

Published: December 30, 2020
https://doi.org/10.1371/journal.pone.0244684

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Preeclampsia
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