Three dimensional cultivation increases chemo- and radioresistance of colorectal cancer cell lines

Jana Koch; Dina Mönch; Annika Maaß; Christian Gromoll; Thomas Hehr; Tobias Leibold; Hans J. Schlitt; Marc-H. Dahlke; Philipp Renner

doi:10.1371/journal.pone.0244513

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Open Access

Peer-reviewed

Research Article

Three dimensional cultivation increases chemo- and radioresistance of colorectal cancer cell lines

Jana Koch,

Roles Project administration, Writing – original draft

Affiliations Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany

https://orcid.org/0000-0001-5978-3992

⨯
Dina Mönch,

Roles Project administration, Writing – original draft

Affiliations Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany
⨯
Annika Maaß,

Roles Investigation, Methodology

Affiliations Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany
⨯
Christian Gromoll,

Roles Resources, Supervision

Affiliations Department of Radiation Therapy, Robert-Bosch-Krankenhaus, Stuttgart, Germany, Department of Radiation Therapy, Marienhospital, Stuttgart, Germany, University of Stuttgart, Stuttgart, Germany
⨯
Thomas Hehr,

Roles Resources, Supervision

Affiliations Department of Radiation Therapy, Robert-Bosch-Krankenhaus, Stuttgart, Germany, Department of Radiation Therapy, Marienhospital, Stuttgart, Germany
⨯
Tobias Leibold,

Roles Writing – review & editing

Affiliation Department of General and Visceral Surgery, Robert-Bosch-Krankenhaus, Stuttgart, Germany
⨯
Hans J. Schlitt,

Roles Writing – review & editing

Affiliation University Medical Centre Regensburg, Regensburg, Germany
⨯
Marc-H. Dahlke,

Roles Conceptualization, Writing – original draft

Affiliation Department of General and Visceral Surgery, Robert-Bosch-Krankenhaus, Stuttgart, Germany
⨯
Philipp Renner

Roles Conceptualization, Writing – original draft

* E-mail: philipp.renner@rbk.de

Affiliations Department of General and Visceral Surgery, Robert-Bosch-Krankenhaus, Stuttgart, Germany, University Medical Centre Regensburg, Regensburg, Germany
⨯

Three dimensional cultivation increases chemo- and radioresistance of colorectal cancer cell lines

Jana Koch,
Dina Mönch,
Annika Maaß,
Christian Gromoll,
Thomas Hehr,
Tobias Leibold,
Hans J. Schlitt,
Marc-H. Dahlke,
Philipp Renner

Published: January 4, 2021
https://doi.org/10.1371/journal.pone.0244513

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