Stat3 oxidation-dependent regulation of gene expression impacts on developmental processes and involves cooperation with Hif-1α

Michela Grillo; Carolyn Palmer; Nadine Holmes; Fei Sang; Andrew C. Larner; Rahul Bhosale; Peter E. Shaw

doi:10.1371/journal.pone.0244255

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Peer-reviewed

Research Article

Stat3 oxidation-dependent regulation of gene expression impacts on developmental processes and involves cooperation with Hif-1α

Michela Grillo ,

Contributed equally to this work with: Michela Grillo, Carolyn Palmer

Roles Investigation, Writing – review & editing

Affiliation School of Life Sciences, University of Nottingham, Queen’s Medical Centre, Nottingham, United Kingdom
⨯
Carolyn Palmer ,

Contributed equally to this work with: Michela Grillo, Carolyn Palmer

Roles Investigation, Writing – review & editing

Affiliation School of Life Sciences, University of Nottingham, Queen’s Medical Centre, Nottingham, United Kingdom
⨯
Nadine Holmes,

Roles Investigation

Affiliation Deep-Seq Unit, School of Life Sciences, University of Nottingham, Queen’s Medical Centre, Nottingham, United Kingdom
⨯
Fei Sang,

Roles Data curation, Formal analysis

Affiliation Deep-Seq Unit, School of Life Sciences, University of Nottingham, Queen’s Medical Centre, Nottingham, United Kingdom
⨯
Andrew C. Larner,

Roles Conceptualization, Supervision

Affiliation Department of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Rahul Bhosale,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation School of Biosciences, University of Nottingham, Sutton Bonington, United Kingdom
⨯
Peter E. Shaw

Roles Conceptualization, Supervision, Writing – original draft

* E-mail: peter.shaw1@nottingham.ac.uk

Affiliation School of Life Sciences, University of Nottingham, Queen’s Medical Centre, Nottingham, United Kingdom

https://orcid.org/0000-0002-2598-4283

⨯

Stat3 oxidation-dependent regulation of gene expression impacts on developmental processes and involves cooperation with Hif-1α

Michela Grillo,
Carolyn Palmer,
Nadine Holmes,
Fei Sang,
Andrew C. Larner,
Rahul Bhosale,
Peter E. Shaw

Published: December 17, 2020
https://doi.org/10.1371/journal.pone.0244255

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Peroxides
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Gene expression
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Oxidation
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Gene regulation
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