A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis

Xiaoming Fan; Yingnyu Gao; Xiaolu Zhang; Haroon Y. Lughmani; David J. Kennedy; Steven T. Haller; Sandrine V. Pierre; Joseph I. Shapiro; Jiang Tian

doi:10.1371/journal.pone.0244065

Loading metrics

Open Access

Peer-reviewed

Research Article

A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis

Xiaoming Fan,

Roles Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Department of Medicine, University of Toledo, Toledo, Ohio, United States of America
⨯
Yingnyu Gao,

Roles Formal analysis, Validation, Writing – original draft, Writing – review & editing

Affiliation Marshall Institute for Interdisciplinary Research, Marshall University, Huntington, West Virginia, United States of America
⨯
Xiaolu Zhang,

Roles Formal analysis, Validation

Affiliation Department of Medicine, University of Toledo, Toledo, Ohio, United States of America
⨯
Haroon Y. Lughmani,

Roles Data curation

Affiliation Department of Medicine, University of Toledo, Toledo, Ohio, United States of America

https://orcid.org/0000-0001-6483-0247

⨯
David J. Kennedy,

Roles Writing – review & editing

Affiliation Department of Medicine, University of Toledo, Toledo, Ohio, United States of America
⨯
Steven T. Haller,

Roles Writing – review & editing

Affiliation Department of Medicine, University of Toledo, Toledo, Ohio, United States of America
⨯
Sandrine V. Pierre,

Roles Writing – review & editing

Affiliation Marshall Institute for Interdisciplinary Research, Marshall University, Huntington, West Virginia, United States of America
⨯
Joseph I. Shapiro,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Joan C. Edwards School of Medicine, Department of Biomedical Sciences, Marshall University, Huntington, West Virginia, United States of America
⨯
Jiang Tian

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: tianj@marshall.edu

Affiliation Joan C. Edwards School of Medicine, Department of Biomedical Sciences, Marshall University, Huntington, West Virginia, United States of America

https://orcid.org/0000-0002-0812-8135

⨯

A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis

Xiaoming Fan,
Yingnyu Gao,
Xiaolu Zhang,
Haroon Y. Lughmani,
David J. Kennedy,
Steven T. Haller,
Sandrine V. Pierre,
Joseph I. Shapiro,
Jiang Tian

Published: December 17, 2020
https://doi.org/10.1371/journal.pone.0244065

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Collagens
Is the Subject Area "Collagens" applicable to this article?

Thanks for your feedback.
Fibrosis
Is the Subject Area "Fibrosis" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Lentivirus
Is the Subject Area "Lentivirus" applicable to this article?

Thanks for your feedback.
RNA sequencing
Is the Subject Area "RNA sequencing" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
RNA extraction
Is the Subject Area "RNA extraction" applicable to this article?

Thanks for your feedback.