Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study

• Raphael Borie,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  https://orcid.org/0000-0002-9906-0024

  ⨯
• Laurent Savale,

  Roles Data curation

  Affiliation Pulmonology Department, Kremlin-Bicêtre University Hospital, AP-HP, Paris-Saclay University, Kremlin-Bicêtre, France

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• Antoine Dossier,

  Roles Data curation

  Affiliation Internal Medicine Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Jade Ghosn,

  Roles Data curation

  Affiliation Infectious Disease Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Camille Taillé,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Benoit Visseaux,

  Roles Data curation

  Affiliation Virology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Kamel Jebreen,

  Roles Formal analysis

  Affiliation Biostatistics and Clinical Research Department, University Hospital Lariboisière, AP-HP, Université de Paris, Paris, France

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• Abourahmane Diallo,

  Roles Formal analysis

  Affiliation Biostatistics and Clinical Research Department, University Hospital Lariboisière, AP-HP, Université de Paris, Paris, France

  ⨯
• Chloe Tesmoingt,

  Roles Data curation, Methodology

  Affiliation Pharmacy Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Lise Morer,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Tiphaine Goletto,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Nathalie Faucher,

  Roles Data curation

  Affiliation Geriatrics Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Linda Hajouji,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Catherine Neukirch,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Mathilde Phillips,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Sandrine Stelianides,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Lila Bouadma,

  Roles Data curation

  Affiliation Medical and infectious Diseases ICU, Intensive Care Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Solenn Brosseau,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Sébastien Ottaviani,

  Roles Data curation

  Affiliation Rheumatology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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• Johan Pluvy,

  Roles Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  https://orcid.org/0000-0002-0129-5803

  ⨯
• Diane Le Pluart,

  Roles Data curation

  Affiliation Infectious Disease Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Marie-Pierre Debray,

  Roles Data curation

  Affiliation Radiology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Agathe Raynaud-Simon,

  Roles Data curation

  Affiliation Pharmacy Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Diane Descamps,

  Roles Data curation

  Affiliation Virology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Antoine Khalil,

  Roles Data curation

  Affiliation Radiology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Jean Francois Timsit,

  Roles Data curation

  Affiliation Medical and infectious Diseases ICU, Intensive Care Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Francois-Xavier Lescure,

  Roles Conceptualization, Data curation

  Affiliation Infectious Disease Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Vincent Descamps,

  Roles Conceptualization, Data curation

  Affiliation Dermatology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Thomas Papo,

  Roles Data curation

  Affiliation Internal Medicine Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Marc Humbert,

  Roles Data curation

  Affiliation Pulmonology Department, Kremlin-Bicêtre University Hospital, AP-HP, Paris-Saclay University, Kremlin-Bicêtre, France

  ⨯
• Bruno Crestani,

  Roles Conceptualization, Data curation

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Philippe Dieude,

  Roles Conceptualization, Data curation, Writing – original draft

  Affiliation Rheumatology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

  ⨯
• Eric Vicaut ,

  Contributed equally to this work with: Eric Vicaut, Gérard Zalcman

  Roles Data curation

  Affiliation Biostatistics and Clinical Research Department, University Hospital Lariboisière, AP-HP, Université de Paris, Paris, France

  ⨯
• Gérard Zalcman ,

  Contributed equally to this work with: Eric Vicaut, Gérard Zalcman

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  * E-mail: gerard.zalcman@aphp.fr

  Affiliation Pulmonology and Thoracic Oncology Department, University Hospital Bichat-Claude Bernard, AP-HP, Université de Paris, Paris, France

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•  [ ... ],
• on behalf of Bichat & Kremlin-Bicêtre AP-HP COVID teams

  ¶The complete membership of the author group can be found in the acknowledgments

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