Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

• Richard L. Cullum,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Chemical Engineering, Auburn University, Auburn, AL, United States of America

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• Lauren M. Lucas,

  Roles Formal analysis, Funding acquisition, Investigation, Project administration, Validation, Visualization, Writing – review & editing

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

  https://orcid.org/0000-0003-0559-1930

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• Jared I. Senfeld,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

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• John T. Piazza,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Biological Sciences, Auburn University, Auburn, AL, United States of America

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• Logan T. Neel,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

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• Kanupriya Whig,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Drug Discovery Division, Southern Research, Birmingham, AL, United States of America

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• Ling Zhai,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Drug Discovery Division, Southern Research, Birmingham, AL, United States of America

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• Mackenzie H. Harris,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Chemical Engineering, Auburn University, Auburn, AL, United States of America

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• Cristina C. Rael,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Biological Sciences, Auburn University, Auburn, AL, United States of America

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• Darby C. Taylor,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Biological Sciences, Auburn University, Auburn, AL, United States of America

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• Laura J. Cook,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Chemistry and Biochemistry, Auburn University, Auburn, AL, United States of America

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• David P. Kaufmann,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

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• Christopher P. Mill,

  Roles Conceptualization, Validation, Writing – review & editing

  Affiliations Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America, Department of Leukemia, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX, United States of America

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• Megan A. Jacobi,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

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• Forrest T. Smith,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

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• Mark Suto,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Drug Discovery Division, Southern Research, Birmingham, AL, United States of America

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• Robert Bostwick,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Drug Discovery Division, Southern Research, Birmingham, AL, United States of America

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• Ram B. Gupta,

  Roles Funding acquisition, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Department of Chemical Engineering, Auburn University, Auburn, AL, United States of America, Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, VA, United States of America

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• Allan E. David,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Department of Chemical Engineering, Auburn University, Auburn, AL, United States of America

  https://orcid.org/0000-0002-5145-4075

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•  [ ... ],
• David J. Riese, II

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: djr0009@auburn.edu

  Affiliation Department of Drug Discovery and Development, Auburn University, Auburn, AL, United States of America

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