Microfluidics and organ-on-a-chip technologies: A systematic review of the methods used to mimic bone marrow

• Gabriel Santos Rosalem,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Mechanical Engineering Graduate Program, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

  ⨯
• Libardo Andrés Gonzáles Torres,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Institute of Science and Technology, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil

  ⨯
• Estevam Barbosa de Las Casas,

  Roles Resources, Writing – review & editing

  Affiliation Department of Structural Engineering, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

  ⨯
• Fernando Augusto Siqueira Mathias,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Biosystems and Genomics Group, René Rachou Institute, Oswaldo Cruz Foundation, Belo Horizonte, Brazil

  ⨯
• Jeronimo Conceição Ruiz ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: maria.gabriela@minas.fiocruz.br (MGRC); jeronimo@minas.fiocruz.br (JCR)

  ¶‡ These are joint senior authors and contributed equally to this work.

  Affiliations Biosystems and Genomics Group, René Rachou Institute, Oswaldo Cruz Foundation, Belo Horizonte, Brazil, Graduate Program in Computational and Systems Biology of the Institute Oswaldo Cruz (PGBCS/IOC/Fiocruz), Rio de Janeiro, Brazil

  ⨯
• Maria Gabriela Reis Carvalho

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: maria.gabriela@minas.fiocruz.br (MGRC); jeronimo@minas.fiocruz.br (JCR)

  ¶‡ These are joint senior authors and contributed equally to this work.

  Affiliation Biosystems and Genomics Group, René Rachou Institute, Oswaldo Cruz Foundation, Belo Horizonte, Brazil

  https://orcid.org/0000-0002-0806-2033

  ⨯