Transferrin receptor regulates malignancies and the stemness of hepatocellular carcinoma-derived cancer stem-like cells by affecting iron accumulation

Chong Xiao; Xi Fu; Yuting Wang; Hong Liu; Yifang Jiang; Ziyi Zhao; Fengming You

doi:10.1371/journal.pone.0243812

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Open Access

Peer-reviewed

Research Article

Transferrin receptor regulates malignancies and the stemness of hepatocellular carcinoma-derived cancer stem-like cells by affecting iron accumulation

Chong Xiao ,

Contributed equally to this work with: Chong Xiao, Xi Fu

Roles Data curation, Investigation, Methodology, Writing – original draft

Affiliation Chengdu University of Traditional Chinese Medicine, Chengdu, China
⨯
Xi Fu ,

Contributed equally to this work with: Chong Xiao, Xi Fu

Roles Investigation, Methodology, Writing – original draft

Affiliation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
⨯
Yuting Wang,

Roles Formal analysis, Investigation, Resources, Software

Affiliation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
⨯
Hong Liu,

Roles Data curation, Investigation, Resources, Software

Affiliation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
⨯
Yifang Jiang,

Roles Investigation, Software

Affiliation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
⨯
Ziyi Zhao ,

Roles Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: zhaoziyi925@163.com (ZZ); youfengming@cdutcm.edu.cn (FY)

Affiliation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China

https://orcid.org/0000-0003-1871-5197

⨯
Fengming You

Roles Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft

* E-mail: zhaoziyi925@163.com (ZZ); youfengming@cdutcm.edu.cn (FY)

Affiliation Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
⨯

Transferrin receptor regulates malignancies and the stemness of hepatocellular carcinoma-derived cancer stem-like cells by affecting iron accumulation

Chong Xiao,
Xi Fu,
Yuting Wang,
Hong Liu,
Yifang Jiang,
Ziyi Zhao,
Fengming You

Published: December 22, 2020
https://doi.org/10.1371/journal.pone.0243812

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