The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer

• Mark Bates ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: batesm1@tcd.ie

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland, Department of Obstetrics and Gynaecology, Trinity College Dublin, Dublin, Ireland

  https://orcid.org/0000-0002-5916-5403

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• Cathy D. Spillane,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland

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• Michael F. Gallagher,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland

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• Amanda McCann,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliation College of Health Sciences, University College Dublin, Belfield, Dublin, Ireland

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• Cara Martin,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland, Department of Pathology, Coombe Women & Infants University Hospital, Dublin, Ireland

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• Gordon Blackshields,

  Roles Data curation, Formal analysis, Software

  Affiliations Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland, Department of Pathology, Coombe Women & Infants University Hospital, Dublin, Ireland

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• Helen Keegan,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland, Department of Pathology, Coombe Women & Infants University Hospital, Dublin, Ireland

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• Luke Gubbins,

  Roles Methodology

  Affiliation College of Health Sciences, University College Dublin, Belfield, Dublin, Ireland

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• Robert Brooks,

  Roles Writing – review & editing

  Affiliation School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia

  https://orcid.org/0000-0003-1535-8999

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• Doug Brooks,

  Roles Writing – original draft, Writing – review & editing

  Affiliation School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia

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• Stavros Selemidis,

  Roles Writing – review & editing

  Affiliation School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology, Bundoora, Australia

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• Sharon O’Toole ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland, Department of Obstetrics and Gynaecology, Trinity College Dublin, Dublin, Ireland

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• John J. O’Leary

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Department of Histopathology, Trinity College Dublin, Dublin, Ireland, Emer Casey Molecular Pathology Research Laboratory, Coombe Women & Infants University Hospital, Dublin, Ireland, Trinity St James’s Cancer Institute, Dublin, Ireland, Department of Pathology, Coombe Women & Infants University Hospital, Dublin, Ireland

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