A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19)

• Cheng-Pin Chen ,

  Contributed equally to this work with: Cheng-Pin Chen, Yi-Chun Lin

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

  Affiliations Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan

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• Yi-Chun Lin ,

  Contributed equally to this work with: Cheng-Pin Chen, Yi-Chun Lin

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

  Affiliations Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan

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• Tsung-Chia Chen,

  Roles Investigation

  Affiliation Department of Internal Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan

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• Ting-Yu Tseng,

  Roles Investigation

  Affiliation Department of Internal Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan

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• Hon-Lai Wong,

  Roles Investigation

  Affiliation Department of Internal Medicine, Keelung Hospital, Ministry of Health and Welfare, Keelung City, Taiwan

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• Cheng-Yu Kuo,

  Roles Investigation

  Affiliation Department of Internal Medicine, Pingtung Hospital, Ministry of Health and Welfare, Pingtung, Taiwan

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• Wu-Pu Lin,

  Roles Investigation

  Affiliation Department of Internal Medicine, Taipei Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan

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• Sz-Rung Huang,

  Roles Investigation

  Affiliation Department of Internal Medicine, Miaoli General Hospital, Ministry of Health and Welfare, Miaoli, Taiwan

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• Wei-Yao Wang,

  Roles Investigation

  Affiliation Department of Internal Medicine, Feng Yuan Hospital, Ministry of Health and Welfare, Taichung, Taiwan

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• Jia-Hung Liao,

  Roles Investigation

  Affiliation Department of Internal Medicine, Nantou Hospital, Ministry of Health and Welfare, Nantou, Taiwan

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• Chung-Shin Liao,

  Roles Investigation

  Affiliation Department of Internal Medicine, Chia Yi Hospital, Ministry of Health and Welfare, Chiayi, Taiwan

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• Yuan-Pin Hung,

  Roles Investigation

  Affiliation Department of Internal Medicine, Tainan Hospital, Ministry of Health and Welfare, Tainan City, Taiwan

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• Tse-Hung Lin,

  Roles Investigation

  Affiliation Department of Internal Medicine, Chang Hua Hospital, Ministry of Health and Welfare, Changhua, Taiwan

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• Tz-Yan Chang,

  Roles Investigation

  Affiliation Department of Internal Medicine, Chang Hua Hospital, Ministry of Health and Welfare, Changhua, Taiwan

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• Chin-Fu Hsiao,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan

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• Yi-Wen Huang,

  Roles Investigation, Supervision

  Affiliations Department of Internal Medicine, Chang Hua Hospital, Ministry of Health and Welfare, Changhua, Taiwan, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan

  https://orcid.org/0000-0001-6097-3910

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• Wei-Sheng Chung,

  Roles Investigation, Supervision

  Affiliations Department of Internal Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan, Department of Health Service Administration, China Medical University, Taichung, Taiwan, Department of Healthcare Administration, Central Taiwan University of Science and Technology, Taichung, Taiwan

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• Chien-Yu Cheng,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, School of Public Health, National Yang-Ming University, Taipei, Taiwan

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• Shu-Hsing Cheng ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – review & editing

  * E-mail: shcheng@mail.tygh.gov.tw

  Affiliations Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, School of Public Health, Taipei Medical University, Taipei, Taiwan

  https://orcid.org/0000-0002-6256-0527

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•  [ ... ],
• on behalf of the Taiwan HCQ Study Group

  ¶Membership of the Taiwan HCQ Study Group is listed in the Acknowledgments.

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