Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes

• José M. Di Diego ,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  * E-mail: didiegoj@gmail.com (JMDD); cantzelevitch@gmail.com (CA)

  ¶‡ These authors share first authorship on this work.

  Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, United States of America

  https://orcid.org/0000-0003-4570-6659

  ⨯
• Bence Patocskai ,

  Roles Formal analysis, Methodology, Writing – review & editing

  ¶‡ These authors share first authorship on this work.

  Affiliation Department of Cardiology, Angiology and Pulmonology, University Hospital, Heidelberg University, Heidelberg, Germany

  ⨯
• Hector Barajas-Martinez ,

  Roles Formal analysis, Investigation, Writing – review & editing

  ¶‡ These authors share first authorship on this work.

  Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, United States of America

  ⨯
• Virág Borbáth,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation First Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

  ⨯
• Michael J. Ackerman,

  Roles Writing – review & editing

  Affiliation Divisions of Heart Rhythm Services and Pediatric Cardiology, Departments of Cardiovascular Medicine, Pediatric and Adolescent Medicine, and Molecular Pharmacology & Experimental Therapeutics, Windland Smith Rice Genetic Heart Rhythm Clinic and Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN, United States of America

  ⨯
• Alexander Burashnikov,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Lankenau Institute for Medical Research, Wynnewood, PA, United States of America, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States of America

  ⨯
• Jérôme Clatot,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Lankenau Institute for Medical Research, Wynnewood, PA, United States of America

  ⨯
• Gui-Rong Li,

  Roles Writing – review & editing

  Affiliation Xiamen Cardiovascular Hospital, Medical School of Xiamen University, Xiamen, China

  ⨯
• Victoria M. Robinson,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Lankenau Institute for Medical Research, Wynnewood, PA, United States of America, The University of Manchester, Manchester, United Kingdom

  ⨯
• Dan Hu,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China

  ⨯
• Charles Antzelevitch

  Roles Conceptualization, Funding acquisition, Resources, Writing – original draft

  * E-mail: didiegoj@gmail.com (JMDD); cantzelevitch@gmail.com (CA)

  Affiliations Lankenau Institute for Medical Research, Wynnewood, PA, United States of America, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States of America, Lankenau Heart Institute, Wynnewood, PA, United States of America

  ⨯