Unraveling the mechanism of recognition of the 3’ splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60

Hsin-hao T. Hsiao; Gregg V. Crichlow; James W. Murphy; Ewa J. Folta-Stogniew; Elias J. Lolis; Demetrios T. Braddock

doi:10.1371/journal.pone.0242725

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Peer-reviewed

Research Article

Unraveling the mechanism of recognition of the 3’ splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60

Hsin-hao T. Hsiao ,

Contributed equally to this work with: Hsin-hao T. Hsiao, Gregg V. Crichlow

Roles Formal analysis, Investigation, Writing – original draft

Current address: American Society for Radiation Oncology, Arlington, Virginia, United States of America

Affiliations Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Gregg V. Crichlow ,

Contributed equally to this work with: Hsin-hao T. Hsiao, Gregg V. Crichlow

Roles Formal analysis, Supervision, Writing – original draft

Current address: Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers University, Piscataway, New Jersey, United States of America

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
James W. Murphy,

Roles Investigation, Supervision

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Ewa J. Folta-Stogniew,

Roles Formal analysis

Affiliation W.M. Keck Biotechnology Research Laboratory, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Elias J. Lolis,

Roles Conceptualization, Formal analysis, Supervision

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Demetrios T. Braddock

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

* E-mail: demetrios.braddock@yale.edu

Affiliation Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, United States of America

https://orcid.org/0000-0002-0541-4689

⨯

Unraveling the mechanism of recognition of the 3’ splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60

Hsin-hao T. Hsiao,
Gregg V. Crichlow,
James W. Murphy,
Ewa J. Folta-Stogniew,
Elias J. Lolis,
Demetrios T. Braddock

Published: November 30, 2020
https://doi.org/10.1371/journal.pone.0242725

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