Evaluation of serum MMP-2 and MMP-3, synovial fluid IL-8, MCP-1, and KC concentrations as biomarkers of stifle osteoarthritis associated with naturally occurring cranial cruciate ligament rupture in dogs

• Sarah Malek ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Writing – original draft, Writing – review & editing

  * E-mail: maleks@purdue.edu

  Affiliation Department of Veterinary Clinical Sciences, Purdue University School of Veterinary Medicine, West Lafayette, Indiana, United States of America

  https://orcid.org/0000-0001-8809-8388

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• Hsin-Yi Weng,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Comparative Pathobiology, Purdue University School of Veterinary Medicine, West Lafayette, Indiana, United States of America

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• Shannon A. Martinson,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada

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• Mark C. Rochat,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Veterinary Clinical Sciences, Purdue University School of Veterinary Medicine, West Lafayette, Indiana, United States of America

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• Romain Béraud,

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Writing – review & editing

  Affiliation Centre Vétérinaire Daubigny, Quebec City, Quebec, Canada

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• Christopher B. Riley

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation School of Veterinary Science, Massey University, Palmerston North, New Zealand

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