Caffeine reverses the unconsciousness produced by light anesthesia in the continued presence of isoflurane in rats

• Aaron P. Fox,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago, Illinois, United States of America

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• Kyle R. Wagner,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Anesthesia and Critical Care, The University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0001-6093-0435

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• Vernon L. Towle,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Writing – review & editing

  Affiliation Department of Neurology, The University of Chicago, Chicago, Illinois, United States of America

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• Kelvin G. Xie,

  Roles Data curation, Formal analysis, Methodology, Software, Validation, Writing – review & editing

  Affiliation Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago, Illinois, United States of America

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• Zheng Xie

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jxie@dacc.uchicago.edu

  Affiliation Department of Anesthesia and Critical Care, The University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0001-8909-8339

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