Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation

Max C. Jacobs; Jacqueline M. Lankelma; Nora S. Wolff; Floor Hugenholtz; Alex F. de Vos; Tom van der Poll; W. Joost Wiersinga

doi:10.1371/journal.pone.0241748

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Open Access

Peer-reviewed

Research Article

Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation

Max C. Jacobs ,

Roles Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: m.c.jacobs@amsterdamumc.nl

Affiliation Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands

https://orcid.org/0000-0001-7854-7936

⨯
Jacqueline M. Lankelma,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands
⨯
Nora S. Wolff,

Roles Methodology, Writing – review & editing

Affiliation Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands
⨯
Floor Hugenholtz,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands
⨯
Alex F. de Vos,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands
⨯
Tom van der Poll,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands, Division of Infectious Diseases, Department of Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands
⨯
W. Joost Wiersinga

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliations Center for Experimental and Molecular Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands, Division of Infectious Diseases, Department of Medicine, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, The Netherlands
⨯

Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation

Max C. Jacobs,
Jacqueline M. Lankelma,
Nora S. Wolff,
Floor Hugenholtz,
Alex F. de Vos,
Tom van der Poll,
W. Joost Wiersinga

Published: November 4, 2020
https://doi.org/10.1371/journal.pone.0241748

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Antibiotics
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Gut bacteria
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Inflammatory diseases
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