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Open Access
Peer-reviewed
Research Article
Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants
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Khaled Heissam ,
Contributed equally to this work with: Khaled Heissam, Nichola Abrehart
Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
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Nichola Abrehart ,
Contributed equally to this work with: Khaled Heissam, Nichola Abrehart
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
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Caroline L. Hoad,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliations Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom, Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom
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Jeff Wright,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
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Alex Menys,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation Motilent Ltd, London, United Kingdom
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Kathryn Murray,
Roles Formal analysis, Writing – review & editing
Affiliations Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom, Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom
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Paul M. Glover,
Roles Methodology, Writing – review & editing
Affiliation Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom
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Geoffrey Hebbard,
Roles Methodology, Writing – review & editing
Affiliation Gastroenterology and Hepatology, The Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia
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Penny A. Gowland,
Roles Methodology, Writing – review & editing
Affiliation Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom
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Jason Baker,
Roles Methodology, Writing – review & editing
Affiliation Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, United States of America
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William L. Hasler,
Roles Methodology, Writing – review & editing
Affiliation Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, United States of America
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Robin C. Spiller,
Roles Methodology, Writing – review & editing
Affiliation Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
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Maura Corsetti,
Roles Methodology, Writing – review & editing
Affiliation Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
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James G. Brasseur,
Roles Methodology, Writing – review & editing
Affiliation Aerospace Engineering Sciences, University of Colorado, Boulder, Colorado, United States of America
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Bart Hens,
Roles Methodology, Writing – review & editing
Affiliations College of Pharmacy, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
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Kerby Shedden,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Statistics, University of Michigan, Ann Arbor, Michigan, United States of America
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Joseph Dickens,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Statistics, University of Michigan, Ann Arbor, Michigan, United States of America
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Deanna M. Mudie,
Roles Methodology, Writing – review & editing
Affiliations College of Pharmacy, University of Michigan, Ann Arbor, Michigan, United States of America, Capsugel, Bend, Oregon, United States of America
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Greg E. Amidon,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
Affiliation College of Pharmacy, University of Michigan, Ann Arbor, Michigan, United States of America
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Gordon L. Amidon,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
Affiliation College of Pharmacy, University of Michigan, Ann Arbor, Michigan, United States of America
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Luca Marciani
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: Luca.Marciani@nottingham.ac.uk
Affiliation Nottigham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom
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Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants
- Khaled Heissam,
- Nichola Abrehart,
- Caroline L. Hoad,
- Jeff Wright,
- Alex Menys,
- Kathryn Murray,
- Paul M. Glover,
- Geoffrey Hebbard,
- Penny A. Gowland,
- Jason Baker
- Published: November 11, 2020
- https://doi.org/10.1371/journal.pone.0241441