Method feasibility for cross-species testing, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for non-human primate serum samples

Nancy A. Niemuth; Thomas L. Rudge Jr.; Karen A. Sankovich; Michael S. Anderson; Nicholas D. Skomrock; Christopher S. Badorrek; Carol L. Sabourin

doi:10.1371/journal.pone.0241016

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Open Access

Peer-reviewed

Research Article

Method feasibility for cross-species testing, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for non-human primate serum samples

Nancy A. Niemuth ,

Roles Conceptualization, Formal analysis, Writing – original draft

* E-mail: niemuth@battelle.org

Affiliation Battelle Biomedical Research Center, West Jefferson, Ohio, United States of America

https://orcid.org/0000-0001-5166-7743

⨯
Thomas L. Rudge Jr.,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Battelle Biomedical Research Center, West Jefferson, Ohio, United States of America
⨯
Karen A. Sankovich,

Roles Investigation

Affiliation Battelle Biomedical Research Center, West Jefferson, Ohio, United States of America
⨯
Michael S. Anderson,

Roles Formal analysis, Writing – review & editing

Affiliation Battelle Biomedical Research Center, West Jefferson, Ohio, United States of America
⨯
Nicholas D. Skomrock,

Roles Formal analysis, Writing – review & editing

Affiliation Battelle Biomedical Research Center, West Jefferson, Ohio, United States of America
⨯
Christopher S. Badorrek,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Contract Support for the U.S. Department of Defense (DOD) Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND) Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Medical (JPM CBRN Medical), Fort Detrick, Maryland, United States of America
⨯
Carol L. Sabourin

Roles Conceptualization, Methodology, Writing – review & editing

Current address: Biomedical Advanced Research and Development Authority (BARDA), Office of the Assistant Secretary for Preparedness and Response (ASPR), U.S. Department of Health and Human Services (HHS), Washington, DC, United States of America.

Affiliation Battelle Biomedical Research Center, West Jefferson, Ohio, United States of America
⨯

Method feasibility for cross-species testing, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for non-human primate serum samples

Nancy A. Niemuth,
Thomas L. Rudge Jr.,
Karen A. Sankovich,
Michael S. Anderson,
Nicholas D. Skomrock,
Christopher S. Badorrek,
Carol L. Sabourin

Published: October 29, 2020
https://doi.org/10.1371/journal.pone.0241016

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