Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells

Joong-Hyun Song; Da-Young Eum; Soon-Yong Park; Yun-Ho Jin; Jae-Woong Shim; Shin-Ji Park; Min-Young Kim; Seong-Jun Park; Kyu Heo; Yoo-Jin Choi

doi:10.1371/journal.pone.0240533

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Open Access

Peer-reviewed

Research Article

Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells

Joong-Hyun Song,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea

https://orcid.org/0000-0001-9961-6451

⨯
Da-Young Eum,

Roles Investigation

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Soon-Yong Park,

Roles Investigation

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Yun-Ho Jin,

Roles Investigation

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Jae-Woong Shim,

Roles Investigation

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Shin-Ji Park,

Roles Methodology

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Min-Young Kim,

Roles Funding acquisition, Methodology

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Seong-Jun Park,

Roles Investigation, Methodology

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Kyu Heo,

Roles Formal analysis, Funding acquisition, Supervision

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea
⨯
Yoo-Jin Choi

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision

* E-mail: cyj5325@dirams.re.kr

Affiliation Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea

https://orcid.org/0000-0003-2621-9433

⨯

Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells

Joong-Hyun Song,
Da-Young Eum,
Soon-Yong Park,
Yun-Ho Jin,
Jae-Woong Shim,
Shin-Ji Park,
Min-Young Kim,
Seong-Jun Park,
Kyu Heo,
Yoo-Jin Choi

Published: October 22, 2020
https://doi.org/10.1371/journal.pone.0240533

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