Expression and function of mechanosensitive ion channels in human valve interstitial cells

Hessah Al-Shammari; Najma Latif; Padmini Sarathchandra; Ann McCormack; Eva A. Rog-Zielinska; Shahzad Raja; Peter Kohl; Magdi H. Yacoub; Rémi Peyronnet; Adrian H. Chester

doi:10.1371/journal.pone.0240532

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Open Access

Peer-reviewed

Research Article

Expression and function of mechanosensitive ion channels in human valve interstitial cells

Hessah Al-Shammari,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation National Heart & Lung Institute, Imperial College London, London, United Kingdom
⨯
Najma Latif,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations National Heart & Lung Institute, Imperial College London, London, United Kingdom, Heart Science Centre, Magdi Yacoub Institute, Harefield, United Kingdom
⨯
Padmini Sarathchandra,

Roles Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation National Heart & Lung Institute, Imperial College London, London, United Kingdom
⨯
Ann McCormack,

Roles Data curation, Methodology, Writing – review & editing

Affiliation Heart Science Centre, Magdi Yacoub Institute, Harefield, United Kingdom
⨯
Eva A. Rog-Zielinska,

Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg, Bad Krozingen, and Faculty of Medicine, University of Freiburg, Freiburg, Germany
⨯
Shahzad Raja,

Roles Resources, Writing – review & editing

Affiliation Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Harefield, United Kingdom
⨯
Peter Kohl,

Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

Affiliation Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg, Bad Krozingen, and Faculty of Medicine, University of Freiburg, Freiburg, Germany
⨯
Magdi H. Yacoub,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliations National Heart & Lung Institute, Imperial College London, London, United Kingdom, Heart Science Centre, Magdi Yacoub Institute, Harefield, United Kingdom
⨯
Rémi Peyronnet ,

Contributed equally to this work with: Rémi Peyronnet, Adrian H. Chester

Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

Affiliations Heart Science Centre, Magdi Yacoub Institute, Harefield, United Kingdom, Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg, Bad Krozingen, and Faculty of Medicine, University of Freiburg, Freiburg, Germany
⨯
Adrian H. Chester

Contributed equally to this work with: Rémi Peyronnet, Adrian H. Chester

Roles Conceptualization, Formal analysis, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: a.chester@imperial.ac.uk

Affiliations National Heart & Lung Institute, Imperial College London, London, United Kingdom, Heart Science Centre, Magdi Yacoub Institute, Harefield, United Kingdom

https://orcid.org/0000-0001-7002-1075

⨯

Expression and function of mechanosensitive ion channels in human valve interstitial cells

Hessah Al-Shammari,
Najma Latif,
Padmini Sarathchandra,
Ann McCormack,
Eva A. Rog-Zielinska,
Shahzad Raja,
Peter Kohl,
Magdi H. Yacoub,
Rémi Peyronnet,
Adrian H. Chester

Published: October 15, 2020
https://doi.org/10.1371/journal.pone.0240532

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