Molecular diagnosis, genetic diversity and drug sensitivity patterns of Mycobacterium tuberculosis strains isolated from tuberculous meningitis patients at a tertiary care hospital in South India

Krishnapriya Krishnakumariamma; Kalaiarasan Ellappan; Muthaiah Muthuraj; Kadhiravan Tamilarasu; Saka Vinod Kumar; Noyal Mariya Joseph

doi:10.1371/journal.pone.0240257

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Peer-reviewed

Research Article

Molecular diagnosis, genetic diversity and drug sensitivity patterns of Mycobacterium tuberculosis strains isolated from tuberculous meningitis patients at a tertiary care hospital in South India

Krishnapriya Krishnakumariamma ,

Contributed equally to this work with: Krishnapriya Krishnakumariamma, Kalaiarasan Ellappan

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India
⨯
Kalaiarasan Ellappan ,

Contributed equally to this work with: Krishnapriya Krishnakumariamma, Kalaiarasan Ellappan

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India
⨯
Muthaiah Muthuraj,

Roles Supervision, Writing – review & editing

Affiliation Intermediate Reference Laboratory, Government Hospital for Chest Diseases, Pondicherry, India
⨯
Kadhiravan Tamilarasu,

Roles Supervision, Writing – review & editing

Affiliation Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India
⨯
Saka Vinod Kumar,

Roles Supervision, Writing – review & editing

Affiliation Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India
⨯
Noyal Mariya Joseph

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: noyaljoseph@yahoo.com

Affiliation Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India

http://orcid.org/0000-0001-6586-2742

⨯

Molecular diagnosis, genetic diversity and drug sensitivity patterns of Mycobacterium tuberculosis strains isolated from tuberculous meningitis patients at a tertiary care hospital in South India

Krishnapriya Krishnakumariamma,
Kalaiarasan Ellappan,
Muthaiah Muthuraj,
Kadhiravan Tamilarasu,
Saka Vinod Kumar,
Noyal Mariya Joseph

Published: October 5, 2020
https://doi.org/10.1371/journal.pone.0240257

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Mycobacterium tuberculosis
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Extensively drug-resistant tuberculosis
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India
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Polymerase chain reaction
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Antibiotic resistance
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DNA extraction
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