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Open Access

Peer-reviewed

Research Article

Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish

Matthew J. Foulkes,

Roles Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Department of Chemistry, The University of Sheffield, Sheffield, United Kingdom, The Bateson Centre, The University of Sheffield, Sheffield, United Kingdom, Department of Infection, Immunity & Cardiovascular Disease, The University of Sheffield, Sheffield, United Kingdom
⨯
Faith H. Tolliday,

Roles Investigation

Affiliations The Bateson Centre, The University of Sheffield, Sheffield, United Kingdom, Department of Infection, Immunity & Cardiovascular Disease, The University of Sheffield, Sheffield, United Kingdom
⨯
Katherine M. Henry,

Roles Methodology, Supervision

Affiliations The Bateson Centre, The University of Sheffield, Sheffield, United Kingdom, Department of Infection, Immunity & Cardiovascular Disease, The University of Sheffield, Sheffield, United Kingdom
⨯
Stephen A. Renshaw,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliations The Bateson Centre, The University of Sheffield, Sheffield, United Kingdom, Department of Infection, Immunity & Cardiovascular Disease, The University of Sheffield, Sheffield, United Kingdom
⨯
Simon Jones

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: simon.jones@sheffield.ac.uk

Affiliation Department of Chemistry, The University of Sheffield, Sheffield, United Kingdom

http://orcid.org/0000-0001-8043-7998

⨯

Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish

Matthew J. Foulkes,
Faith H. Tolliday,
Katherine M. Henry,
Stephen A. Renshaw,
Simon Jones

x

Published: October 6, 2020
https://doi.org/10.1371/journal.pone.0240231

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Neutrophils
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Inflammation
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Zebrafish
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Larvae
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Chemical synthesis
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Apoptosis
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Toxicity
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Isomers
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