Exploring MRI based radiomics analysis of intratumoral spatial heterogeneity in locally advanced nasopharyngeal carcinoma treated with intensity modulated radiotherapy

Farhan Akram; Ping En Koh; Fuqiang Wang; Siqin Zhou; Sze Huey Tan; Mahsa Paknezhad; Sojeong Park; Tiffany Hennedige; Choon Hua Thng; Hwee Kuan Lee; Kiattisa Sommat

doi:10.1371/journal.pone.0240043

Loading metrics

Open Access

Peer-reviewed

Research Article

Exploring MRI based radiomics analysis of intratumoral spatial heterogeneity in locally advanced nasopharyngeal carcinoma treated with intensity modulated radiotherapy

Farhan Akram,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing

Affiliation A*STAR (Agency for Science, Technology and Research), Bioinformatics Institute, Singapore
⨯
Ping En Koh,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliation Divisions of Radiation Oncology, National Cancer Centre Singapore, Singapore
⨯
Fuqiang Wang,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Divisions of Radiation Oncology, National Cancer Centre Singapore, Singapore
⨯
Siqin Zhou,

Roles Formal analysis, Methodology, Visualization, Writing – review & editing

Affiliation Divisions of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore
⨯
Sze Huey Tan,

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Divisions of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore
⨯
Mahsa Paknezhad,

Roles Conceptualization, Investigation, Methodology, Writing – review & editing

Affiliation A*STAR (Agency for Science, Technology and Research), Bioinformatics Institute, Singapore
⨯
Sojeong Park,

Roles Investigation, Writing – review & editing

Affiliation A*STAR (Agency for Science, Technology and Research), Bioinformatics Institute, Singapore
⨯
Tiffany Hennedige,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Divisions of Oncologic Imaging and Epidemiological Sciences, National Cancer Centre Singapore, Singapore
⨯
Choon Hua Thng,

Roles Data curation, Supervision, Writing – review & editing

Affiliation Divisions of Oncologic Imaging and Epidemiological Sciences, National Cancer Centre Singapore, Singapore
⨯
Hwee Kuan Lee,

Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation A*STAR (Agency for Science, Technology and Research), Bioinformatics Institute, Singapore
⨯
Kiattisa Sommat

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: kiattisa.sommat@singhealth.com.sg

Affiliation Divisions of Radiation Oncology, National Cancer Centre Singapore, Singapore

http://orcid.org/0000-0003-4050-2841

⨯

Exploring MRI based radiomics analysis of intratumoral spatial heterogeneity in locally advanced nasopharyngeal carcinoma treated with intensity modulated radiotherapy

Farhan Akram,
Ping En Koh,
Fuqiang Wang,
Siqin Zhou,
Sze Huey Tan,
Mahsa Paknezhad,
Sojeong Park,
Tiffany Hennedige,
Choon Hua Thng,
Hwee Kuan Lee

Published: October 5, 2020
https://doi.org/10.1371/journal.pone.0240043

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Magnetic resonance imaging
Is the Subject Area "Magnetic resonance imaging" applicable to this article?

Thanks for your feedback.
Nasopharyngeal carcinoma
Is the Subject Area "Nasopharyngeal carcinoma" applicable to this article?

Thanks for your feedback.
Radiation therapy
Is the Subject Area "Radiation therapy" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Oncology
Is the Subject Area "Oncology" applicable to this article?

Thanks for your feedback.
Principal component analysis
Is the Subject Area "Principal component analysis" applicable to this article?

Thanks for your feedback.