Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology

Peter R. W. Gowler; Paul I. Mapp; James J. Burston; Mohsen Shahtaheri; David A. Walsh; Victoria Chapman

doi:10.1371/journal.pone.0239663

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Open Access

Peer-reviewed

Research Article

Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology

Peter R. W. Gowler,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Pain Centre Versus Arthritis, School of Life Sciences, Queen’s Medical Centre, University of Nottingham, Nottingham, United Kingdom

http://orcid.org/0000-0001-7242-8725

⨯
Paul I. Mapp,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Pain Centre Versus Arthritis, Academic Rheumatology, City Hospital, University of Nottingham, Nottingham, United Kingdom
⨯
James J. Burston,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation Pain Centre Versus Arthritis, School of Life Sciences, Queen’s Medical Centre, University of Nottingham, Nottingham, United Kingdom
⨯
Mohsen Shahtaheri,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Pain Centre Versus Arthritis, Academic Rheumatology, City Hospital, University of Nottingham, Nottingham, United Kingdom
⨯
David A. Walsh,

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

Affiliation Pain Centre Versus Arthritis, Academic Rheumatology, City Hospital, University of Nottingham, Nottingham, United Kingdom
⨯
Victoria Chapman

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Victoria.chapman@nottingham.ac.uk

Affiliation Pain Centre Versus Arthritis, School of Life Sciences, Queen’s Medical Centre, University of Nottingham, Nottingham, United Kingdom
⨯

Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology

Peter R. W. Gowler,
Paul I. Mapp,
James J. Burston,
Mohsen Shahtaheri,
David A. Walsh,
Victoria Chapman

Published: September 29, 2020
https://doi.org/10.1371/journal.pone.0239663

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Pain
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Skeletal joints
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Rats
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Surgical and invasive medical procedures
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Mice
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Osteoarthritis
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Cartilage
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Animal behavior
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