Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients

Cecilia Drakskog; Nele de Klerk; Johanna Westerberg; Elina Mäki-Torkko; Susanna Kumlien Georén; Lars Olaf Cardell

doi:10.1371/journal.pone.0239161

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Peer-reviewed

Research Article

Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients

Cecilia Drakskog ,

Contributed equally to this work with: Cecilia Drakskog, Nele de Klerk

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Writing – original draft, Writing – review & editing

Affiliation The Division of ENT Diseases, CLINTEC, Karolinska Institutet, Stockholm, Sweden
⨯
Nele de Klerk ,

Contributed equally to this work with: Cecilia Drakskog, Nele de Klerk

Roles Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

Affiliation The Division of ENT Diseases, CLINTEC, Karolinska Institutet, Stockholm, Sweden
⨯
Johanna Westerberg,

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliations Division of Neuro and Inflammation Science, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden, Department of Otorhinolaryngology in Linköping, Anaesthetics, Operations and Specialty Surgery Centre, Region Östergötland, Linköping, Sweden
⨯
Elina Mäki-Torkko,

Roles Conceptualization, Writing – review & editing

Affiliations Division of Neuro and Inflammation Science, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden, Department of Otorhinolaryngology in Linköping, Anaesthetics, Operations and Specialty Surgery Centre, Region Östergötland, Linköping, Sweden, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
⨯
Susanna Kumlien Georén,

Roles Data curation, Project administration, Supervision, Writing – review & editing

Affiliation The Division of ENT Diseases, CLINTEC, Karolinska Institutet, Stockholm, Sweden
⨯
Lars Olaf Cardell

Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

* E-mail: lars-olaf.cardell@ki.se

Affiliations The Division of ENT Diseases, CLINTEC, Karolinska Institutet, Stockholm, Sweden, Department of ENT Diseases, Karolinska University Hospital, Stockholm, Sweden

http://orcid.org/0000-0003-0538-9580

⨯

Extensive qPCR analysis reveals altered gene expression in middle ear mucosa from cholesteatoma patients

Cecilia Drakskog,
Nele de Klerk,
Johanna Westerberg,
Elina Mäki-Torkko,
Susanna Kumlien Georén,
Lars Olaf Cardell

Published: September 11, 2020
https://doi.org/10.1371/journal.pone.0239161

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Middle ear
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Surgical and invasive medical procedures
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Gene expression
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Ear infections
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