Combined PCR and MAT improves the early diagnosis of the biphasic illness leptospirosis

Noraini Philip; Norliza Bahtiar Affendy; Siti Norbaya Masri; Muhamad Yazli Yuhana; Leslie Thian Lung Than; Zamberi Sekawi; Vasantha Kumari Neela

doi:10.1371/journal.pone.0239069

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Open Access

Peer-reviewed

Research Article

Combined PCR and MAT improves the early diagnosis of the biphasic illness leptospirosis

Noraini Philip,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft

Affiliation Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
⨯
Norliza Bahtiar Affendy,

Roles Investigation, Methodology, Project administration

Affiliation Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
⨯
Siti Norbaya Masri,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

Affiliation Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
⨯
Muhamad Yazli Yuhana,

Roles Data curation, Resources

Affiliation Infectious Diseases Unit, Internal Medicine Department, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia

http://orcid.org/0000-0002-3917-6316

⨯
Leslie Thian Lung Than,

Roles Funding acquisition, Resources

Affiliation Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
⨯
Zamberi Sekawi,

Roles Conceptualization, Funding acquisition

Affiliation Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
⨯
Vasantha Kumari Neela

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: vasantha@upm.edu.my

Affiliation Department of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
⨯

Combined PCR and MAT improves the early diagnosis of the biphasic illness leptospirosis

Noraini Philip,
Norliza Bahtiar Affendy,
Siti Norbaya Masri,
Muhamad Yazli Yuhana,
Leslie Thian Lung Than,
Zamberi Sekawi,
Vasantha Kumari Neela

Published: September 11, 2020
https://doi.org/10.1371/journal.pone.0239069

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Leptospirosis
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Polymerase chain reaction
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Diagnostic medicine
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Blood
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Leptospira
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Malaysia
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Nested polymerase chain reaction
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Serology
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