Computational approaches to support comparative analysis of multiparametric tests: Modelling versus Training

• John M. S. Bartlett ,

  Contributed equally to this work with: John M. S. Bartlett, Jane Bayani

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: John.Bartlett@oicr.on.ca (JMSB); Elizabeth.Kornaga@albertahealthservices.ca (ENK)

  Affiliations Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada, Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada, Edinburgh Cancer Research Centre, Edinburgh, United Kingdom

  http://orcid.org/0000-0002-0347-3888

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• Jane Bayani ,

  Contributed equally to this work with: John M. S. Bartlett, Jane Bayani

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada

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• Elizabeth N. Kornaga ,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  * E-mail: John.Bartlett@oicr.on.ca (JMSB); Elizabeth.Kornaga@albertahealthservices.ca (ENK)

  Affiliation Tom Baker Cancer Centre, Calgary, Alberta, Canada

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• Patrick Danaher,

  Roles Data curation, Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada

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• Cheryl Crozier,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada

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• Tammy Piper,

  Roles Data curation, Writing – review & editing

  Affiliation Edinburgh Cancer Research Centre, Edinburgh, United Kingdom

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• Cindy Q. Yao,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada

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• Janet A. Dunn,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – review & editing

  Affiliation Warwick Medical School, University of Warwick, Coventry, United Kingdom

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• Paul C. Boutros,

  Roles Formal analysis, Supervision, Writing – review & editing

  Current address: Department of Human Genetics & Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California, United States of America

  Affiliations Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario, Canada

  http://orcid.org/0000-0003-0553-7520

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• Robert C. Stein,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation UCL (University College London) and National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom

  http://orcid.org/0000-0003-2969-0415

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• OPTIMA Trial Management Group

  ¶Membership of the OPTIMA Trial Management Group is provided in the Acknowledgments.

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