Impact of different consensus definition criteria on sepsis diagnosis in a cohort of critically ill patients—Insights from a new mathematical probabilistic approach to mortality-based validation of sepsis criteria

• Franz-Simon Centner ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  * E-mail: Franz-Simon.Centner@umm.de

  Affiliation Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany

  http://orcid.org/0000-0002-7455-1361

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• Jochen J. Schoettler,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany

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• Anna-Meagan Fairley,

  Roles Validation, Writing – review & editing

  Affiliation Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany

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• Holger A. Lindner,

  Roles Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  Affiliation Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany

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• Verena Schneider-Lindner,

  Roles Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  Affiliations Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany, Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada

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• Christel Weiss,

  Roles Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Department of Biomedical Informatics of the Heinrich-Lanz-Center, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany

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• Manfred Thiel,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany

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• Michael Hagmann

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft

  Affiliation Interdisciplinary Center for Scientific Computing, Heidelberg University, Heidelberg, Germany

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