Variable patterns of mutation density among Na_V1.1, Na_V1.2 and Na_V1.6 point to channel-specific functional differences associated with childhood epilepsy

• Alejandra C. Encinas ,

  Contributed equally to this work with: Alejandra C. Encinas, Joseph C. Watkins

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Graduate Program in Genetics, University of Arizona, Tucson, Arizona, United States of America

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• Joseph C. Watkins ,

  Contributed equally to this work with: Alejandra C. Encinas, Joseph C. Watkins

  Roles Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Mathematics, University of Arizona, Tucson, Arizona, United States of America

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• Iris Arenas Longoria,

  Roles Formal analysis

  Current address: Department of Mathematics, Queen’s University, Kingston, Canada

  Affiliation Department of Mathematics, University of Arizona, Tucson, Arizona, United States of America

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• J. P. Johnson Jr,

  Roles Writing – review & editing

  Affiliation Xenon Pharmaceuticals, Burnaby, BC, Canada

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• Michael F. Hammer

  Roles Conceptualization, Data curation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mfh@email.arizona.edu

  Affiliation Department of Neurology, University of Arizona, Tucson, Arizona, United States of America

  http://orcid.org/0000-0003-0172-429X

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