Temporal transcriptome analysis suggest modulation of multiple pathways and gene network involved in cell-cell interaction during early phase of high altitude exposure

Priya Gaur; Supriya Saini; Koushik Ray; Kushubakova Nadira Asanbekovna; Almaz Akunov; Abdirashit Maripov; Akpay Sarybaev; Shashi Bala Singh; Bhuvnesh Kumar; Praveen Vats

doi:10.1371/journal.pone.0238117

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Open Access

Peer-reviewed

Research Article

Temporal transcriptome analysis suggest modulation of multiple pathways and gene network involved in cell-cell interaction during early phase of high altitude exposure

Priya Gaur,

Roles Conceptualization, Data curation, Methodology, Writing – original draft

Affiliation Defence Institute of Physiology and Allied Sciences, Delhi, India
⨯
Supriya Saini,

Roles Formal analysis, Writing – review & editing

Affiliation Defence Institute of Physiology and Allied Sciences, Delhi, India
⨯
Koushik Ray,

Roles Conceptualization, Supervision

Affiliation Defence Institute of Physiology and Allied Sciences, Delhi, India
⨯
Kushubakova Nadira Asanbekovna,

Roles Formal analysis, Methodology

Affiliation Kyrgyz Indian Mountain Biomedical Research Centre, Bishkek, Kyrgyz Republic, Kyrgyzstan
⨯
Almaz Akunov,

Roles Project administration, Resources, Supervision

Affiliation Kyrgyz Indian Mountain Biomedical Research Centre, Bishkek, Kyrgyz Republic, Kyrgyzstan
⨯
Abdirashit Maripov,

Roles Project administration, Resources, Supervision

Affiliation Kyrgyz Indian Mountain Biomedical Research Centre, Bishkek, Kyrgyz Republic, Kyrgyzstan
⨯
Akpay Sarybaev ,

Roles Funding acquisition, Project administration, Resources, Supervision

* E-mail: drvatsp@gmail.com, drvatsp@dipas.drdo.in (PV); ak_sar777@mail.ru (AS)

Affiliation Kyrgyz Indian Mountain Biomedical Research Centre, Bishkek, Kyrgyz Republic, Kyrgyzstan
⨯
Shashi Bala Singh,

Roles Visualization, Writing – review & editing

Affiliation National Institute of Pharmaceutical Education & Research, Hyderabad, Telangana, India
⨯
Bhuvnesh Kumar,

Roles Project administration, Supervision, Writing – review & editing

Affiliation Defence Institute of Physiology and Allied Sciences, Delhi, India
⨯
Praveen Vats

Roles Conceptualization, Data curation, Investigation, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: drvatsp@gmail.com, drvatsp@dipas.drdo.in (PV); ak_sar777@mail.ru (AS)

Affiliation Defence Institute of Physiology and Allied Sciences, Delhi, India

http://orcid.org/0000-0002-0105-5041

⨯

Temporal transcriptome analysis suggest modulation of multiple pathways and gene network involved in cell-cell interaction during early phase of high altitude exposure

Priya Gaur,
Supriya Saini,
Koushik Ray,
Kushubakova Nadira Asanbekovna,
Almaz Akunov,
Abdirashit Maripov,
Akpay Sarybaev,
Shashi Bala Singh,
Bhuvnesh Kumar,
Praveen Vats

Published: September 10, 2020
https://doi.org/10.1371/journal.pone.0238117

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Gene expression
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Blood pressure
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Hypoxia
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Altitude sickness
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Gene ontologies
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RNA sequencing
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Cell enumeration techniques
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Centrality
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