Bio-activating ultrafine grain titanium: RNA sequencing reveals enhanced mechano-activation of osteoconduction on nanostructured substrates

• Rebecca A. Reiss ,

  Contributed equally to this work with: Rebecca A. Reiss, Terry C. Lowe

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rebecca.reiss@nmt.edu

  Affiliation Biology Department, New Mexico Institution of Mining and Technology, Socorro, New Mexico, United States of America

  http://orcid.org/0000-0002-9884-0440

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• Terry C. Lowe ,

  Contributed equally to this work with: Rebecca A. Reiss, Terry C. Lowe

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation George S. Ansell Department of Metallurgical and Materials Engineering, Colorado School of Mines, Golden, Colorado, United States of America

  http://orcid.org/0000-0001-9288-1076

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• Johnny A. Sena ,

  Roles Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation National Center for Genome Resources, Santa Fe, New Mexico, United States of America

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• Oleg Makhnin ,

  Roles Formal analysis

  ¶‡ These authors also contributed equally to this work.

  Affiliation Mathematics Department, New Mexico Institute of Mining and Technology, Socorro, New Mexico, United States of America

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• Melanie C. Connick ,

  Roles Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Biology Department, New Mexico Institution of Mining and Technology, Socorro, New Mexico, United States of America

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• Patrick E. Illescas ,

  Roles Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Biology Department, New Mexico Institution of Mining and Technology, Socorro, New Mexico, United States of America

  http://orcid.org/0000-0003-3111-4302

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• Casey F. Davis

  Roles Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation George S. Ansell Department of Metallurgical and Materials Engineering, Colorado School of Mines, Golden, Colorado, United States of America

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