Ketamine/xylazine and barbiturates modulate microglial morphology and motility differently in a mouse model

• Ines Hristovska ,

  Contributed equally to this work with: Ines Hristovska, Franck Verdonk

  Roles Data curation, Formal analysis, Visualization, Writing – original draft

  Affiliations Equipe Synaptopathies et Autoanticorps (SynatAc), Institut NeuroMyoGène, INSERM U1217/UMR CNRS 5310, Lyon, France, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France

  http://orcid.org/0000-0003-4779-4103

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• Franck Verdonk ,

  Contributed equally to this work with: Ines Hristovska, Franck Verdonk

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Unité Neuropathologie Expérimentale, Département Infection et Epidémiologie, Institut Pasteur, Paris, France, Department d’anesthésiologie et de Soins Intensifs, Hôpital Saint Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France, Sorbonne Université, Paris, France, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, United States of America

  http://orcid.org/0000-0001-7061-5594

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• Jean-Christophe Comte,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France, Equipe Processus d’oubli et Dynamique Corticale, Centre de Recherche en Neuroscience de Lyon (CRNL), INSERM U1028, CNRS UMR5292, Lyon, France

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• Eileen S. Tsai,

  Roles Writing – review & editing

  Affiliation Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, United States of America

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• Virginie Desestret,

  Roles Conceptualization, Writing – review & editing

  Affiliations Equipe Synaptopathies et Autoanticorps (SynatAc), Institut NeuroMyoGène, INSERM U1217/UMR CNRS 5310, Lyon, France, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France, Centre maladies rares sur les syndromes neurologiques paranéoplasiques, Hospices Civils de Lyon, Lyon, France

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• Jérôme Honnorat,

  Roles Conceptualization, Writing – review & editing

  Affiliations Equipe Synaptopathies et Autoanticorps (SynatAc), Institut NeuroMyoGène, INSERM U1217/UMR CNRS 5310, Lyon, France, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France, Centre maladies rares sur les syndromes neurologiques paranéoplasiques, Hospices Civils de Lyon, Lyon, France

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• Fabrice Chrétien ,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  * E-mail: fabrice.chretien@pasteur.fr (FC); olivier.pascual@inserm.fr (OP)

  Affiliations Unité Neuropathologie Expérimentale, Département Infection et Epidémiologie, Institut Pasteur, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Laboratoire Hospitalo-Universitaire de Neuropathologie, Centre Hospitalier Sainte Anne, Paris, France

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• Olivier Pascual

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: fabrice.chretien@pasteur.fr (FC); olivier.pascual@inserm.fr (OP)

  Affiliations Equipe Synaptopathies et Autoanticorps (SynatAc), Institut NeuroMyoGène, INSERM U1217/UMR CNRS 5310, Lyon, France, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France

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