The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer

• Claire A. Walsh,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  ⨯
• Nina Akrap,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  ⨯
• Elena Garre,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  http://orcid.org/0000-0002-3827-4977

  ⨯
• Ylva Magnusson,

  Roles Investigation

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  ⨯
• Hannah Harrison,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Paterson Institute for Cancer Research, The Christie NHS Foundation Trust, Manchester, United Kingdom

  ⨯
• Daniel Andersson,

  Roles Methodology, Writing – review & editing

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  ⨯
• Emma Jonasson,

  Roles Data curation, Formal analysis

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  ⨯
• Svanheidur Rafnsdottir,

  Roles Investigation, Resources

  Affiliation Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden

  ⨯
• Hani Choudhry,

  Roles Investigation, Resources

  Affiliation Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia

  ⨯
• Francesca Buffa,

  Roles Data curation, Formal analysis, Methodology

  Affiliation The Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, United Kingdom

  ⨯
• Jiannis Ragoussis,

  Roles Data curation, Formal analysis, Methodology

  Affiliation McGill University and Genome Quebec Innovation Centre, Montreal, Canada

  ⨯
• Anders Ståhlberg,

  Roles Conceptualization, Funding acquisition

  Affiliations Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden, Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden

  http://orcid.org/0000-0003-4243-0191

  ⨯
• Adrian Harris,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation The Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, United Kingdom

  ⨯
• Göran Landberg

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: goran.landberg@gu.se

  Affiliation Sahlgrenska Cancer Center, Department of Laboratory Medicine, Gothenburg, Sweden

  ⨯