Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model

• Cheng-Yu Yang ,

  Contributed equally to this work with: Cheng-Yu Yang, Chang-Huei Tsao, Cheng-Chih Hsieh

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation School of Dentistry, National Defense Medical Center, Taipei, Taiwan, R.O.C

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• Chang-Huei Tsao ,

  Contributed equally to this work with: Cheng-Yu Yang, Chang-Huei Tsao, Cheng-Chih Hsieh

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, R.O.C, Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, R.O.C

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• Cheng-Chih Hsieh ,

  Contributed equally to this work with: Cheng-Yu Yang, Chang-Huei Tsao, Cheng-Chih Hsieh

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacy Practice, Tri-Service General Hospital, Taipei, Taiwan, R.O.C

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• Chih-Kung Lin,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Division of Anatomic Pathology, Taipei Tzu Chi Hospital, Taipei, Taiwan, R.O.C

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• Chun-Shu Lin,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation

  Affiliations Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Centre, Taipei, Taiwan, R.O.C, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, R.O.C

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• Yu-Hsuan Li,

  Roles Data curation, Formal analysis, Resources

  Affiliations School of Dentistry, National Defense Medical Center, Taipei, Taiwan, R.O.C, Department of Oral and Maxillofacial Surgery, Tri-Service General Hospital, Taipei, Taiwan, R.O.C

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• Wei-Chin Chang,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation

  Affiliations School of Dentistry, National Defense Medical Center, Taipei, Taiwan, R.O.C, Department of Oral and Maxillofacial Surgery, Tri-Service General Hospital, Taipei, Taiwan, R.O.C

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• Jen-Chen Cheng,

  Roles Data curation, Funding acquisition, Resources

  Affiliations School of Dentistry, National Defense Medical Center, Taipei, Taiwan, R.O.C, Department of Oral and Maxillofacial Surgery, Tri-Service General Hospital, Taipei, Taiwan, R.O.C

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• Gu-Jiun Lin,

  Roles Formal analysis, Methodology, Project administration, Validation

  Affiliation Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, R.O.C

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• Huey-Kang Sytwu,

  Roles Formal analysis, Methodology, Supervision, Validation

  Affiliations Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, R.O.C, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County, Taiwan, R.O.C

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• Yin-Lai Wang ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: h6183@yahoo.com.tw (YWC); dentowanglai@yahoo.com.tw (YLW)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Dentistry, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan, R.O.C

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• Yuan-Wu Chen

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: h6183@yahoo.com.tw (YWC); dentowanglai@yahoo.com.tw (YLW)

  ¶‡ These authors also contributed equally to this work.

  Affiliations School of Dentistry, National Defense Medical Center, Taipei, Taiwan, R.O.C, Department of Oral and Maxillofacial Surgery, Tri-Service General Hospital, Taipei, Taiwan, R.O.C

  http://orcid.org/0000-0003-1927-7088

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