Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites

Margarida Ressurreição; James A. Thomas; Stephanie D. Nofal; Christian Flueck; Robert W. Moon; David A. Baker; Christiaan van Ooij

doi:10.1371/journal.pone.0235798

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Peer-reviewed

Research Article

Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites

Margarida Ressurreição,

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – review & editing

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
James A. Thomas,

Roles Formal analysis, Funding acquisition, Investigation, Visualization, Writing – review & editing

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom

http://orcid.org/0000-0002-1991-1838

⨯
Stephanie D. Nofal,

Roles Formal analysis, Investigation, Writing – review & editing

Current address: Signalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Christian Flueck,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Robert W. Moon,

Roles Formal analysis, Funding acquisition, Investigation, Writing – review & editing

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
David A. Baker ,

Roles Formal analysis, Funding acquisition, Supervision, Writing – review & editing

* E-mail: David.Baker@lshtm.ac.uk (DAB); Christiaan.vanOoij@lshtm.ac.uk (CVO)

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Christiaan van Ooij

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

* E-mail: David.Baker@lshtm.ac.uk (DAB); Christiaan.vanOoij@lshtm.ac.uk (CVO)

Affiliation Department of Infection Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom

http://orcid.org/0000-0002-6099-6183

⨯

Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites

Margarida Ressurreição,
James A. Thomas,
Stephanie D. Nofal,
Christian Flueck,
Robert W. Moon,
David A. Baker,
Christiaan van Ooij

Published: July 16, 2020
https://doi.org/10.1371/journal.pone.0235798
See the preprint

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