High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients

• Yuka Nozaki ,

  Contributed equally to this work with: Yuka Nozaki, Hitomi Motomura, Shoma Tamori

  Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan

  ⨯
• Hitomi Motomura ,

  Contributed equally to this work with: Yuka Nozaki, Hitomi Motomura, Shoma Tamori

  Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliations Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan

  ⨯
• Shoma Tamori ,

  Contributed equally to this work with: Yuka Nozaki, Hitomi Motomura, Shoma Tamori

  Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliations Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan

  ⨯
• Yumiko Kimura,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

  ⨯
• Chotaro Onaga,

  Roles Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliation Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

  ⨯
• Shotaro Kanai,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

  ⨯
• Yuka Ishihara,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

  ⨯
• Ayaka Ozaki,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

  ⨯
• Yasushi Hara,

  Roles Formal analysis, Investigation, Resources, Writing – review & editing

  Affiliation Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan

  http://orcid.org/0000-0002-0528-3252

  ⨯
• Yohsuke Harada,

  Roles Resources, Validation, Writing – review & editing

  Affiliation Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan

  ⨯
• Yasunari Mano,

  Roles Validation, Writing – review & editing

  Affiliations Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan

  ⨯
• Tsugumichi Sato,

  Roles Validation, Writing – review & editing

  Affiliations Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan

  ⨯
• Keiko Sato,

  Roles Resources, Validation, Writing – review & editing

  Affiliations Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan, Faculty of Science and technology, Tokyo University of Science, Chiba, Japan

  ⨯
• Kazunori Sasaki,

  Roles Resources, Writing – review & editing

  Affiliation Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, Kanagawa, Japan

  ⨯
• Hitoshi Ishiguro,

  Roles Resources, Writing – review & editing

  Affiliations Department of Urology, Yokohama City University Graduate School of Medicine, Kanagawa, Japan, Photocatalyst Group, Kanagawa Institute of Industrial Science and Technology, Kanagawa, Japan

  ⨯
• Shigeo Ohno,

  Roles Resources, Writing – review & editing

  Affiliation Department of Molecular Biology, Yokohama City University Graduate School of Medical Science, Kanagawa, Japan

  ⨯
•  [ ... ],
• Kazunori Akimoto

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: akimoto@rs.tus.ac.jp

  Affiliations Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, Translational Research Center, Research Institute for Science & Technology, Tokyo University of Science, Chiba, Japan

  http://orcid.org/0000-0003-0618-1765

  ⨯
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