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Open Access
Peer-reviewed
Research Article
The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer
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Raffaella Soldi,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Writing – original draft
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Tithi Ghosh Halder,
Roles Data curation, Investigation, Methodology, Software, Validation, Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Alexis Weston,
Roles Data curation, Investigation, Methodology, Software
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Trason Thode,
Roles Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Kevin Drenner,
Roles Investigation, Software, Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Rhonda Lewis,
Roles Conceptualization, Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Mohan R. Kaadige,
Roles Conceptualization, Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Shreyesi Srivastava,
Roles Writing – review & editing
Affiliation HonorHealth Clinical Research Institute, Scottsdale, Arizona, United States of America
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Sherin Daniel Ampanattu,
Roles Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Ryan Rodriguez del Villar,
Roles Methodology, Writing – review & editing
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Jessica Lang,
Roles Writing – review & editing
Affiliation Integrated Cancer Genomics Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Hariprasad Vankayalapati,
Roles Data curation
Affiliation Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, United States of America
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Bernard Weissman,
Roles Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America
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Jeffrey M. Trent,
Roles Conceptualization
Affiliation Integrated Cancer Genomics Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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William P. D. Hendricks,
Roles Conceptualization, Writing – review & editing
Affiliation Integrated Cancer Genomics Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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Sunil Sharma
Roles Conceptualization, Project administration, Supervision, Writing – review & editing
* E-mail: ssharma@tgen.org
Affiliation Applied Cancer Research and Drug Discovery Division, Translational Genomics Research Institute (TGen) of City of Hope, Phoenix, Arizona, United States of America
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The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer
- Raffaella Soldi,
- Tithi Ghosh Halder,
- Alexis Weston,
- Trason Thode,
- Kevin Drenner,
- Rhonda Lewis,
- Mohan R. Kaadige,
- Shreyesi Srivastava,
- Sherin Daniel Ampanattu,
- Ryan Rodriguez del Villar
![PLOS](/resource/img/logo-plos.png)
- Published: July 10, 2020
- https://doi.org/10.1371/journal.pone.0235705
- See the preprint