Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels

Katsuhiko Sato; Hayato Hikita; Yuta Myojin; Kenji Fukumoto; Kazuhiro Murai; Sadatsugu Sakane; Takeshi Tamura; Takuo Yamai; Yasutoshi Nozaki; Teppei Yoshioka; Takahiro Kodama; Minoru Shigekawa; Ryotaro Sakamori; Tomohide Tatsumi; Tetsuo Takehara

doi:10.1371/journal.pone.0235573

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Open Access

Peer-reviewed

Research Article

Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels

Katsuhiko Sato,

Roles Conceptualization, Data curation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Hayato Hikita,

Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Yuta Myojin,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Kenji Fukumoto,

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Kazuhiro Murai,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Sadatsugu Sakane,

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Takeshi Tamura,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Takuo Yamai,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Yasutoshi Nozaki,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Teppei Yoshioka,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Takahiro Kodama,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Minoru Shigekawa,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Ryotaro Sakamori,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan

http://orcid.org/0000-0002-1580-607X

⨯
Tomohide Tatsumi,

Roles Conceptualization, Data curation

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Tetsuo Takehara

Roles Conceptualization, Data curation, Writing – review & editing

* E-mail: takehara@gh.med.osaka-u.ac.jp

Affiliation Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
⨯

Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels

Katsuhiko Sato,
Hayato Hikita,
Yuta Myojin,
Kenji Fukumoto,
Kazuhiro Murai,
Sadatsugu Sakane,
Takeshi Tamura,
Takuo Yamai,
Yasutoshi Nozaki,
Teppei Yoshioka

Published: July 1, 2020
https://doi.org/10.1371/journal.pone.0235573

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