Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models

Joerg Neddens; Magdalena Daurer; Stefanie Flunkert; Kerstin Beutl; Tina Loeffler; Lauren Walker; Johannes Attems; Birgit Hutter-Paier

doi:10.1371/journal.pone.0235543

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Open Access

Peer-reviewed

Research Article

Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models

Joerg Neddens ,

Contributed equally to this work with: Joerg Neddens, Magdalena Daurer

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliation QPS Austria GmbH, Grambach, Austria
⨯
Magdalena Daurer ,

Contributed equally to this work with: Joerg Neddens, Magdalena Daurer

Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

Affiliation QPS Austria GmbH, Grambach, Austria
⨯
Stefanie Flunkert ,

Roles Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: stefanie.flunkert@qps.com

Affiliation QPS Austria GmbH, Grambach, Austria

http://orcid.org/0000-0003-3806-3907

⨯
Kerstin Beutl,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliations QPS Austria GmbH, Grambach, Austria, FH Joanneum Graz, Graz, Austria
⨯
Tina Loeffler,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation QPS Austria GmbH, Grambach, Austria
⨯
Lauren Walker,

Roles Conceptualization, Validation, Writing – review & editing

Affiliation Translational and Clinical Research Institute and Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom
⨯
Johannes Attems,

Roles Conceptualization, Validation, Writing – review & editing

Affiliation Translational and Clinical Research Institute and Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom
⨯
Birgit Hutter-Paier

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation QPS Austria GmbH, Grambach, Austria

http://orcid.org/0000-0003-3699-2227

⨯

Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models

Joerg Neddens,
Magdalena Daurer,
Stefanie Flunkert,
Kerstin Beutl,
Tina Loeffler,
Lauren Walker,
Johannes Attems,
Birgit Hutter-Paier

Published: July 9, 2020
https://doi.org/10.1371/journal.pone.0235543

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