Constant compression decreases vascular bud and VEGFA expression in a rabbit vertebral endplate ex vivo culture model

Jia-Wen Zhan; Shang-Quan Wang; Min-Shan Feng; Xu Wei; Jie Yu; Xun-Lu Yin; Tao Han; Li-Guo Zhu

doi:10.1371/journal.pone.0234747

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Open Access

Peer-reviewed

Research Article

Constant compression decreases vascular bud and VEGFA expression in a rabbit vertebral endplate ex vivo culture model

Jia-Wen Zhan,

Roles Conceptualization, Data curation, Writing – original draft

Affiliations General Orthopedics Department, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China, Key Laboratory of Beijing of Palasy Technology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Shang-Quan Wang,

Roles Investigation, Methodology, Supervision

Affiliation General Orthopedics Department, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Min-Shan Feng,

Roles Data curation, Investigation, Methodology

Affiliations Key Laboratory of Beijing of Palasy Technology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China, Spine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Xu Wei,

Roles Data curation, Formal analysis, Methodology

Affiliation Scientific Research Office, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Jie Yu,

Roles Data curation, Investigation, Software, Validation

Affiliation Spine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Xun-Lu Yin,

Roles Formal analysis, Investigation

Affiliations Key Laboratory of Beijing of Palasy Technology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China, Spine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Tao Han,

Roles Data curation, Formal analysis, Investigation

Affiliations General Orthopedics Department, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China, Key Laboratory of Beijing of Palasy Technology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Li-Guo Zhu

Roles Conceptualization, Project administration, Writing – review & editing

* E-mail: 532414151@qq.com

Affiliations Key Laboratory of Beijing of Palasy Technology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China, Spine Department 2, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China

http://orcid.org/0000-0003-4061-8668

⨯

Constant compression decreases vascular bud and VEGFA expression in a rabbit vertebral endplate ex vivo culture model

Jia-Wen Zhan,
Shang-Quan Wang,
Min-Shan Feng,
Xu Wei,
Jie Yu,
Xun-Lu Yin,
Tao Han,
Li-Guo Zhu

Published: June 25, 2020
https://doi.org/10.1371/journal.pone.0234747

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