Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

• Uwe Hansen ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  * E-mail: paul.bishop@manchester.ac.uk (PNB); uhansen@uni-muenster.de (UH)

  Affiliations Department of Physiological Chemistry & Pathobiochemistry, University Hospital of Münster, Münster, Germany, Institute of Musculoskeletal Medicine, University Hospital Münster, Münster, Germany

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• David F. Holmes,

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Peter Bruckner,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Physiological Chemistry & Pathobiochemistry, University Hospital of Münster, Münster, Germany

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• Paul N. Bishop

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Writing – original draft

  * E-mail: paul.bishop@manchester.ac.uk (PNB); uhansen@uni-muenster.de (UH)

  Affiliations Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom

  http://orcid.org/0000-0001-7937-7932

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