Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

• Kiran Chaudhari ,

  Contributed equally to this work with: Kiran Chaudhari, Jianmei Wang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Writing – original draft

  Affiliation Department of Pharmacology and Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Jianmei Wang ,

  Contributed equally to this work with: Kiran Chaudhari, Jianmei Wang

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  Affiliation Pharmaceutical analysis core lab, College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Yong Xu,

  Roles Data curation, Validation

  Affiliation Department of Pharmacology and Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Ali Winters,

  Roles Data curation

  Affiliation Department of Pharmacology and Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Linshu Wang,

  Roles Data curation

  Affiliation Department of Pharmacology and Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Xiaowei Dong,

  Roles Validation

  Affiliation Pharmaceutical Sciences, College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Eric Y. Cheng,

  Roles Validation

  Affiliation Pharmaceutical Sciences, College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Ran Liu,

  Roles Project administration

  Affiliation Department of Pharmacology and Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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• Shao-Hua Yang

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: shaohua.yang@unthsc.edu

  Affiliation Department of Pharmacology and Neuroscience, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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