Genetic variants in NECTIN4 encoding an adhesion molecule are associated with continued opioid use

Chiu-Ping Fang; Tung-Hsia Liu; Ren-Hua Chung; Hsiao-Hui Tsou; Hsiang-Wei Kuo; Sheng-Chang Wang; Chia-Chen Liu; Shu Chih Liu; Andrew C. H. Chen; Yu-Li Liu

doi:10.1371/journal.pone.0234549

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Open Access

Peer-reviewed

Research Article

Genetic variants in NECTIN4 encoding an adhesion molecule are associated with continued opioid use

Chiu-Ping Fang,

Roles Writing – original draft

Affiliation Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
⨯
Tung-Hsia Liu,

Roles Formal analysis

Affiliation Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
⨯
Ren-Hua Chung,

Roles Formal analysis

Affiliation Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan
⨯
Hsiao-Hui Tsou,

Roles Formal analysis

Affiliations Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan, Graduate Institute of Biostatistics, China Medical University, Taichung, Taiwan
⨯
Hsiang-Wei Kuo,

Roles Data curation, Methodology

Affiliation Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
⨯
Sheng-Chang Wang,

Roles Data curation

Affiliation Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
⨯
Chia-Chen Liu,

Roles Data curation

Affiliation Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
⨯
Shu Chih Liu,

Roles Data curation

Affiliation Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
⨯
Andrew C. H. Chen,

Roles Writing – review & editing

Affiliations Department of Psychiatry, the Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York, United States of America, The Feinstein Institute for Medical Research, Hofstra Northwell School of Medicine at Hofstra University, Manhasset, New York, United States of America
⨯
Yu-Li Liu

Roles Funding acquisition, Supervision

* E-mail: ylliou@nhri.org.tw

Affiliations Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan, Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan

http://orcid.org/0000-0001-7519-2965

⨯

Genetic variants in NECTIN4 encoding an adhesion molecule are associated with continued opioid use

Chiu-Ping Fang,
Tung-Hsia Liu,
Ren-Hua Chung,
Hsiao-Hui Tsou,
Hsiang-Wei Kuo,
Sheng-Chang Wang,
Chia-Chen Liu,
Shu Chih Liu,
Andrew C. H. Chen,
Yu-Li Liu

Published: June 18, 2020
https://doi.org/10.1371/journal.pone.0234549

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Single nucleotide polymorphisms
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Heroin
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Introns
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Blood plasma
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