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Open Access
Peer-reviewed
Research Article
An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis
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Daniel J. García-Domínguez ,
Contributed equally to this work with: Daniel J. García-Domínguez, Lourdes Hontecillas-Prieto
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: dgarcia-ibis@us.es (DJGD); enrique.alava.sspa@juntadeandalucia.es (EDA)
Affiliation Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla/CIBERONC, Seville, Spain
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Lourdes Hontecillas-Prieto ,
Contributed equally to this work with: Daniel J. García-Domínguez, Lourdes Hontecillas-Prieto
Roles Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla/CIBERONC, Seville, Spain
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Eduardo Andrés León ,
Roles Formal analysis, Investigation, Software, Writing – review & editing
¶‡ These authors also contributed equally to this work.
Affiliation Bioinformatics Unit, Instituto de Parasitología y Biomedicina “López-Neyra”, Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain
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Sara Sánchez-Molina ,
Roles Investigation, Validation, Writing – review & editing
¶‡ These authors also contributed equally to this work.
Affiliation Developmental Tumor Biology Laboratory, Institut de Recerca Pediàtrica—Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain
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Pablo Rodríguez-Núñez,
Roles Investigation, Writing – review & editing
Affiliation Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla/CIBERONC, Seville, Spain
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Francisco J. Morón,
Roles Formal analysis, Investigation, Software, Writing – review & editing
Affiliation Genomics Core Facility, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, Sevilla, Spain
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Nabil Hajji,
Roles Conceptualization, Visualization
Affiliation Division of Brain Sciences, The John Fulcher Molecular Neuro-Oncology Laboratory, Imperial College London, London, England, United Kingdom
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Carlos Mackintosh,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Vitro SA, Granada, Spain
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Enrique de Álava
Roles Conceptualization, Supervision, Writing – review & editing
* E-mail: dgarcia-ibis@us.es (DJGD); enrique.alava.sspa@juntadeandalucia.es (EDA)
Affiliations Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla/CIBERONC, Seville, Spain, Department of Normal and Pathological Cytology and Histology, School of Medicine, University of Seville, Seville, Spain
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An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis
- Daniel J. García-Domínguez,
- Lourdes Hontecillas-Prieto,
- Eduardo Andrés León,
- Sara Sánchez-Molina,
- Pablo Rodríguez-Núñez,
- Francisco J. Morón,
- Nabil Hajji,
- Carlos Mackintosh,
- Enrique de Álava
- Published: June 5, 2020
- https://doi.org/10.1371/journal.pone.0234243