NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture

• Denise C. Cornelius ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: dcornelius@umc.edu

  Affiliations Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America, Department of Pharmacology & Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

  http://orcid.org/0000-0002-6730-6499

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• Olivia K. Travis,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Pharmacology & Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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• Robert W. Tramel,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

  http://orcid.org/0000-0002-5489-1086

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• Marivee Borges-Rodriguez,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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• Cedar H. Baik,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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• Mallory Greer,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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• Chelsea A. Giachelli,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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• Geilda A. Tardo,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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• Jan M. Williams

  Roles Formal analysis, Funding acquisition, Software, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology & Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America, Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

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