Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes

• Julie A. D. Van ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: julie.van@mail.utoronto.ca

  Affiliations Institute of Medical Science, University of Toronto, Toronto, Canada, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada

  http://orcid.org/0000-0003-2419-7736

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• Sergi Clotet-Freixas,

  Roles Methodology, Writing – review & editing

  Affiliation Toronto General Hospital Research Institute, University Health Network, Toronto, Canada

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• Anne-Christin Hauschild,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Krembil Research Institute, University Health Network, Toronto, Canada, Department of Mathematics & Computer Science, University of Marburg, Marburg, Germany

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• Ihor Batruch,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine and Pathobiology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Canada

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• Igor Jurisica,

  Roles Software, Writing – review & editing

  Affiliations Krembil Research Institute, University Health Network, Toronto, Canada, Department of Computer Science, University of Toronto, Toronto, Canada, Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia

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• Yesmino Elia,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Hospital for Sick Children, Toronto, Ontario, Canada

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• Farid H. Mahmud,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Hospital for Sick Children, Toronto, Ontario, Canada

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• Etienne Sochett,

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliation Hospital for Sick Children, Toronto, Ontario, Canada

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• Eleftherios P. Diamandis,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliations Department of Laboratory Medicine and Pathobiology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Canada, Department of Clinical Biochemistry, University Health Network, University of Toronto, Toronto, Canada

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• James W. Scholey,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Institute of Medical Science, University of Toronto, Toronto, Canada, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada, Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada

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• Ana Konvalinka

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Institute of Medical Science, University of Toronto, Toronto, Canada, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada, Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada

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