Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex

Sarah C. Garrett-Thomson; Aldo Massimi; Elena V. Fedorov; Jeffrey B. Bonanno; Lisa Scandiuzzi; Brandan Hillerich; Ronald D. Seidel III; James D. Love; Scott J. Garforth; Chandan Guha; Steven C. Almo

doi:10.1371/journal.pone.0233578

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Open Access

Peer-reviewed

Research Article

Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex

Sarah C. Garrett-Thomson ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

* E-mail: steven.almo@einsteinmed.org (SA); sarah.garrett@einsteinmed.org (SG)

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

http://orcid.org/0000-0002-3073-1571

⨯
Aldo Massimi,

Roles Investigation, Methodology

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Elena V. Fedorov,

Roles Resources

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Jeffrey B. Bonanno,

Roles Formal analysis, Investigation

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Lisa Scandiuzzi,

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Brandan Hillerich,

Roles Investigation, Methodology

Affiliation Cue BioPharma Inc., Cambridge, Massachusetts, United States of America
⨯
Ronald D. Seidel III,

Roles Conceptualization, Investigation, Methodology

Affiliation Cue BioPharma Inc., Cambridge, Massachusetts, United States of America
⨯
James D. Love,

Roles Investigation, Methodology

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Scott J. Garforth,

Roles Resources

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Chandan Guha,

Roles Supervision

Affiliation Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯
Steven C. Almo

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: steven.almo@einsteinmed.org (SA); sarah.garrett@einsteinmed.org (SG)

Affiliation Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯

Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex

Sarah C. Garrett-Thomson,
Aldo Massimi,
Elena V. Fedorov,
Jeffrey B. Bonanno,
Lisa Scandiuzzi,
Brandan Hillerich,
Ronald D. Seidel III,
James D. Love,
Scott J. Garforth,
Chandan Guha

Published: June 4, 2020
https://doi.org/10.1371/journal.pone.0233578

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