Postoperative analgesia using dezocine alleviates depressive symptoms after colorectal cancer surgery: A randomized, controlled, double-blind trial

Peng Zhao; Zhuoxi Wu; Chunrui Li; Guiying Yang; Jinping Ding; Kai Wang; Mingming Wang; Lijuan Feng; Guangyou Duan; Hong Li

doi:10.1371/journal.pone.0233412

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Open Access

Peer-reviewed

Research Article

Postoperative analgesia using dezocine alleviates depressive symptoms after colorectal cancer surgery: A randomized, controlled, double-blind trial

Peng Zhao,

Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Zhuoxi Wu,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Chunrui Li,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Guiying Yang,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Jinping Ding,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Kai Wang,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Mingming Wang,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Lijuan Feng,

Roles Investigation

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Guangyou Duan ,

Contributed equally to this work with: Guangyou Duan, Hong Li

Roles Conceptualization, Formal analysis, Methodology, Validation, Writing – review & editing

* E-mail: dgy1986anesthesia@126.com (GYD); lh78553@163.com (HL)

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China
⨯
Hong Li

Contributed equally to this work with: Guangyou Duan, Hong Li

Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

* E-mail: dgy1986anesthesia@126.com (GYD); lh78553@163.com (HL)

Affiliation Department of Anesthesiology, Second Affiliated Hospital, Army Medical University, Chongqing, China

http://orcid.org/0000-0002-1338-0829

⨯

Postoperative analgesia using dezocine alleviates depressive symptoms after colorectal cancer surgery: A randomized, controlled, double-blind trial

Peng Zhao,
Zhuoxi Wu,
Chunrui Li,
Guiying Yang,
Jinping Ding,
Kai Wang,
Mingming Wang,
Lijuan Feng,
Guangyou Duan,
Hong Li

Published: May 26, 2020
https://doi.org/10.1371/journal.pone.0233412

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Surgical and invasive medical procedures
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Depression
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Serotonin
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Analgesia
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Norepinephrine
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Sleep
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Colorectal cancer
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Pain
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